GLL 398

CAS No. 2077980-80-2

GLL 398( —— )

Catalog No. M29017 CAS No. 2077980-80-2

GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 393 Get Quote
10MG 590 Get Quote
25MG 1060 Get Quote
50MG 1591 Get Quote
100MG 2387 Get Quote
200MG 3580 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    GLL 398
  • Note
    Research use only, not for human use.
  • Brief Description
    GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
  • Description
    GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.(In Vitro):GLL398 exhibits a strong dose-dependent binding profile for the estrogen receptor with a Y537S point mutation with an IC50 of 29.5 nM.
  • In Vitro
    GLL398 is a boron-modified GW5638 analog.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    Estrogen Receptor/ERR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2077980-80-2
  • Formula Weight
    398.26
  • Molecular Formula
    C25H23BO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (627.73 mM)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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