
GLL 398
CAS No. 2077980-80-2
GLL 398( —— )
Catalog No. M29017 CAS No. 2077980-80-2
GLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 393 | Get Quote |
![]() ![]() |
10MG | 590 | Get Quote |
![]() ![]() |
25MG | 1060 | Get Quote |
![]() ![]() |
50MG | 1591 | Get Quote |
![]() ![]() |
100MG | 2387 | Get Quote |
![]() ![]() |
200MG | 3580 | Get Quote |
![]() ![]() |
500MG | Get Quote | Get Quote |
![]() ![]() |
1G | Get Quote | Get Quote |
![]() ![]() |
Biological Information
-
Product NameGLL 398
-
NoteResearch use only, not for human use.
-
Brief DescriptionGLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.
-
DescriptionGLL 398 is an orally active and selective degrader of estrogen receptor with an IC50 of 1.14 nM. GLL 398 blocks tumor growth in xenograft breast cancer models.(In Vitro):GLL398 exhibits a strong dose-dependent binding profile for the estrogen receptor with a Y537S point mutation with an IC50 of 29.5 nM.
-
In VitroGLL398 is a boron-modified GW5638 analog.
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetEstrogen Receptor/ERR
-
RecptorEstrogen Receptor/ERR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2077980-80-2
-
Formula Weight398.26
-
Molecular FormulaC25H23BO4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (627.73 mM)
-
SMILES——
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog



related products
-
Norgestrel
Norgestrel is a synthetic progestin commonly used alone or in combination with an estrogen for contraception.
-
Estropipate
Estropipate is a form of estrogen.
-
Anwuligan
Anwuligan is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.